Simulation of Feedforward-Feedback Control of Dissolved Oxygen (DO) of Microbial Repeated Fed-batch Culture
نویسندگان
چکیده
Fed-batch culture is often used in industry, and dissolved oxygen (DO) concentration control is important in fermentation process control. DO control is often applied by using feedback (FB) control strategy. But, feedforward-feedback (FFFB) control has the advantage in dealing with the time-varying characteristics resulting from cell growth during the fermentation process. Mathematical modeling and computer simulation is a useful tool in the analysis of the control system. In this paper, we model and simulate the FF-FB DO control and FB substrate control of repeated fed-batch culture process. The results show the feasibility of the control strategy and are useful for control system development and process analyses and optimization.
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